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Robert W Hoffman Selected Research

Small Nuclear Ribonucleoproteins (snRNP)

11/2010T cell vaccination therapy in an induced model of anti-RNP autoimmune glomerulonephritis.
6/2008CD4+ T cells target epitopes residing within the RNA-binding domain of the U1-70-kDa small nuclear ribonucleoprotein autoantigen and have restricted TCR diversity in an HLA-DR4-transgenic murine model of mixed connective tissue disease.
2/2006A murine model of mixed connective tissue disease induced with U1 small nuclear RNP autoantigen.
9/2002T cell immunity in connective tissue disease patients targets the RNA binding domain of the U1-70kDa small nuclear ribonucleoprotein.

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Robert W Hoffman Research Topics

Disease

9Systemic Lupus Erythematosus (Libman-Sacks Disease)
10/2020 - 02/2003
6Mixed Connective Tissue Disease (MCTD)
09/2008 - 03/2002
4Autoimmune Diseases (Autoimmune Disease)
05/2007 - 01/2004
3Lung Diseases (Lung Disease)
11/2010 - 02/2006
2Psoriasis (Pustulosis Palmaris et Plantaris)
12/2014 - 07/2012
2Inflammation (Inflammations)
12/2014 - 07/2012
2Nephritis
11/2010 - 05/2007
2Glomerulonephritis
11/2010 - 02/2006
2Connective Tissue Diseases (Connective Tissue Disease)
07/2004 - 09/2002
1Exanthema (Rash)
01/2018
1Infections
01/2018
1Arthritis (Polyarthritis)
01/2018
1Hyperplasia
07/2012
1Ischemia
05/2007
1Mesenteric Ischemia
05/2007
1Lung Injury
05/2007
1Sialadenitis
05/2007
1malar rash
03/2002

Drug/Important Bio-Agent (IBA)

6AutoantigensIBA
06/2008 - 09/2002
4Small Nuclear Ribonucleoproteins (snRNP)IBA
11/2010 - 09/2002
4AntibodiesIBA
05/2007 - 03/2002
4AutoantibodiesIBA
05/2007 - 07/2004
3baricitinibIBA
10/2020 - 01/2018
3AntigensIBA
11/2010 - 07/2004
3EpitopesIBA
06/2008 - 02/2003
2ixekizumabIBA
12/2014 - 07/2012
2Interleukin-17 (Interleukin 17)IBA
12/2014 - 07/2012
2Peptides (Polypeptides)IBA
07/2012 - 09/2002
2U1 small nuclear RNAIBA
06/2008 - 02/2006
1Janus KinasesIBA
01/2018
1Monoclonal AntibodiesIBA
01/2017
1tabalumabIBA
01/2017
1Immunoglobulin G (IgG)IBA
01/2017
1CytokinesIBA
07/2012
1VaccinesIBA
11/2010
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
11/2010
1Proteasome Endopeptidase Complex (Proteasome)IBA
09/2008
1T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
06/2008
1Toll-Like Receptors (Toll-Like Receptor)IBA
05/2007
1RNA (Ribonucleic Acid)IBA
05/2007
1SS-A antigen (Ro antigen)IBA
05/2007
1RibonucleoproteinsIBA
05/2007
1Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA
07/2004
1U1 Small Nuclear RibonucleoproteinIBA
09/2002
1SS-A antibodiesIBA
03/2002

Therapy/Procedure

2Therapeutics
01/2018 - 11/2010